How does Hyaluronidase Work?

Hyaluronidase works as an enzyme to temporarily break down hyaluronic acid which is found naturally in the body. This makes it easier for injection of fluids to be administered, and effective absorption of the fluids into the skin and tissue. Buy Hyaluronidase 1500 IU

Hyaluronidase additionally aids the body to  reabsorb blood and fluids from the tissues, in the case of a large bruise.

What’s in the box?

  • Hyaluronidase enzyme (active ingredient)
  • 10 amps (1500iu)

What are the benefits of Hyaluronidase?

  • Aid in the penetration of fluids during subcutaneous and intramuscular injections
  • Hyaluronidase can be directly added to the fluid or solution that is being infected into the skin
  • Aids absorption of a subcutaneous infusion, where Hyaluronidase is injected beforehand into the site of injection where the injection is to be administered
  • To aid the body to reabsorb fluids or blood in haematomas or extravasation, where Hyaluronidase is mixed with saline or water before being injected at the site of injection
  • Breaks down Hyaluronic acid which is present between cells to help them adhesive together. This is a temporary action and helps the quick absorption of fluid injections.


While Hyalase injections are usually well tolerated, certain patients should not be injected with hyaluronidase. Those who are allergic or hypersensitive to hyaluronidase should never undergo treatment with this injectable solution. Additionally, caution should be used in patients who are pregnant or breastfeeding.

Please note that Hyalase should never be used for intravenous injections or for anesthetic procedures in cases of unexplained premature labour. Moreover, it should not be used to reduce the swelling of infected or malignant bites or stings.

In case of overdose, patients must seek immediate medical assistance. Buy Hyaluronidase 1500 IU


  • Localized hives, erythema, and swelling;
  • Chills;
  • Nausea, dizziness, and vomiting;
  • Tachycardia;
  • And hypotension.


Hyalase has been reported to be physically incompatible with heparin, adrenaline, benzodiazepines, phenytoin, and frusemide.


Although rare, side effects have been known to occur with injection of Hyalase. If these are experienced, patients should seek immediate medical attention. Please note that hyaluronidase has been reported to enhance the occurrence of adverse effects in co-administered drugs.

The following side effects may occur:

  • Oedema
  • Blurred vision
  • Allergy
  • Hypersensitivity
  • Local irritation, bleeding, and bruising
  • Infection
  • Eye disorders




The main active component of Hyalase is hyaluronidase, an enzyme that is naturally produced in the body. This compound breaks down hyaluronan, which works as a structural and biochemical supporter of the cells. By weakening hyaluronan, hyaluronidase increases the absorbency of bodily tissues. As such, it is often used in tandem with injectable drugs (including anesthetics) to hasten their dispersal into the injection site.

Hyaluronidase is also used to help the body reabsorb excess fluids and blood from the skin tissues. As such, it is excellent for treating extravasation and hematomas.